Investigating the lung using time-resolved diffuse optics

Antonio Pifferi; Andrea Farina; Alberto Dalla Mora; Pranav Lanka; Sanathana Konugolu Venkata Sekar; Massimo Miniati; Paola Taroni

doi:10.1117/12.2578858

5 March 2021 Investigating the lung using time-resolved diffuse optics

Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Pranav Lanka, Sanathana Konugolu Venkata Sekar, Massimo Miniati, Paola Taroni

Author Affiliations +

Proceedings Volume 11639, Optical Tomography and Spectroscopy of Tissue XIV; 116390M (2021) https://doi.org/10.1117/12.2578858
Event: SPIE BiOS, 2021, Online Only

Abstract

We have addressed the challenge of investigating the lung using diffuse optics along four different directions, namely: 1) broadband time-domain diffuse optics (TD-DO) in the 600-1100 nm range to derive the mean chest optical properties; 2) Monte Carlo simulations to investigate the depth-sensitivity of TD-DO measurements assuming a layered structure of the chest; 3) single-wavelength TD-DO using a high power pulsed laser on 5 healthy volunteers on a dynamic protocol; 4) single-wavelength TD-DO measurements using a novel large area Silicon Photomultiplier (SIPM) detector module permitting acquisitions at 12 cm source-detector distance.

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Citation Download Citation

Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Pranav Lanka, Sanathana Konugolu Venkata Sekar, Massimo Miniati, and Paola Taroni "Investigating the lung using time-resolved diffuse optics", Proc. SPIE 11639, Optical Tomography and Spectroscopy of Tissue XIV, 116390M (5 March 2021); https://doi.org/10.1117/12.2578858

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