Propagation of acousto-optic signal in multi-layer biological tissue by using COMSOL multiphysics

Huihuang Deng; Haiyang Song; Huanchang Liu; Yuxin Lu; Lili Zhu

doi:10.1117/12.2601277

9 October 2021 Propagation of acousto-optic signal in multi-layer biological tissue by using COMSOL multiphysics

Huihuang Deng, Haiyang Song, Huanchang Liu, Yuxin Lu, Lili Zhu

Proceedings Volume 11900, Optics in Health Care and Biomedical Optics XI; 1190024 (2021) https://doi.org/10.1117/12.2601277
Event: SPIE/COS Photonics Asia, 2021, Nantong, JS, China

Conference Poster

Abstract

Biological tissue is a multiple random scattering medium. The study of the propagation of acousto-optic signals in biological tissues is an important and complex issue in acousto-optical tomography(AOT). In this paper, the finite element simulation software COMSOL Multiphysics is used to simulate the propagation of acousto-optic signal modulated by ultrasound in double-layer tissue. The effects of different types of ultrasounds on acousto-optic signals in tissues are studied. The influence of the optical properties of the target tissue and non-target tissue on the acousto-optic signal in the double-layered tissue is also discussed. The simulation results show that the waveform of the acousto-optic signal is very similar to that of the ultrasonic wave. The acousto-optic signal presents a periodic variation as the ultrasonic frequency changes. The peak-to-peak value and average value of the acousto-optic signal are affected by the optical properties of double-layer tissue. However, the modulation depth of the acousto-optic signal only depends on the optical characteristics of the tissue in the ultrasound focal zone (target tissue), and has nothing to do with the optical characteristics of the tissue outside the ultrasound zone (non-target tissue). The modulation depth has a good antiinterference performance, which is conducive to image processing and reconstruction in AOT.

Citation Download Citation

Huihuang Deng, Haiyang Song, Huanchang Liu, Yuxin Lu, and Lili Zhu "Propagation of acousto-optic signal in multi-layer biological tissue by using COMSOL multiphysics", Proc. SPIE 11900, Optics in Health Care and Biomedical Optics XI, 1190024 (9 October 2021); https://doi.org/10.1117/12.2601277

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