Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis

Suzanna Freer; Cong Sui; Liam M. Grover; Stephen M. Hanham; Miguel Navarro-Cía

doi:10.1117/12.2610249

7 March 2022 Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis

Suzanna Freer, Cong Sui, Liam M. Grover, Stephen M. Hanham, Miguel Navarro-Cía

Proceedings Volume 11949, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX; 1194904 (2022) https://doi.org/10.1117/12.2610249
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Water is a fundamental component of many biological systems. The ability to detect water therefore provides great insight into system functionality, particularly in the development of disease. In this work, the high interaction of terahertz radiation with water, paired with the dependence of the dynamics of water molecules with varying temperature, is utilised to monitor changes in the composition of bone tissue. Heterotopic ossification (HO) bone samples and deionised free water are measured using terahertz time-domain spectroscopy for varying environmental temperatures, for prospective use in disease diagnosis.

Conference Presentation

Citation Download Citation

Suzanna Freer, Cong Sui, Liam M. Grover, Stephen M. Hanham, and Miguel Navarro-Cía "Temperature dependent hyperspectral terahertz imaging of human bone for disease diagnosis", Proc. SPIE 11949, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX, 1194904 (7 March 2022); https://doi.org/10.1117/12.2610249

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