Evaluation of cerebral perfusion and edema after ischemic stroke utilizing SS-OCT

Ning Ding; Jian Liu; Yao Yu; Yi Wang; Yuqian Zhao; Zhenhe Ma

doi:10.1117/12.2688486

27 November 2023 Evaluation of cerebral perfusion and edema after ischemic stroke utilizing SS-OCT

Ning Ding, Jian Liu, Yao Yu, Yi Wang, Yuqian Zhao, Zhenhe Ma

Proceedings Volume 12770, Optics in Health Care and Biomedical Optics XIII; 1277035 (2023) https://doi.org/10.1117/12.2688486
Event: SPIE/COS Photonics Asia, 2023, Beijing, China

Conference Poster

Abstract

Ischemic cerebral edema (CE) is a major cause of death in patients with ischemic stroke. Detecting CE and local cerebral blood perfusion (LCBP) simultaneously may offer valuable insights for treating ischemic stroke (IS). In this work, a swept-source optical coherence tomography (SS-OCT) system was established to evaluate the photo-thrombosis ischemia mouse model for a long time. The progressive state of CE and LCBP was quantified and analyzed. Preliminary studies revealed that edema significantly affected LCBP with a clear spatial dependence, the edema area increased sharply when the LCBP dropped to around 60% of the initial value.

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Ning Ding, Jian Liu, Yao Yu, Yi Wang, Yuqian Zhao, and Zhenhe Ma "Evaluation of cerebral perfusion and edema after ischemic stroke utilizing SS-OCT", Proc. SPIE 12770, Optics in Health Care and Biomedical Optics XIII, 1277035 (27 November 2023); https://doi.org/10.1117/12.2688486

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