Presentation
13 March 2024 Laser bioprinting for engineering urinary bladder tissue
Author Affiliations +
Proceedings Volume 12817, Advanced Photonics in Urology 2024; 1281704 (2024) https://doi.org/10.1117/12.3001512
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
For decades the need for organs for transplantation by far exceeds their availability, costing the lives of patients in desperate need for a transplant. This need has acted as driving force for the growth of the tissue engineering field. For the most part, tissue engineering utilizes scaffolds made of decellularized tissues or synthetic and natural hydrogels that can be polymerized. More recently, bioprinting has emerged as a robust alternative for precise placing of cells onto scaffolds or into polymers. Laser bioprinting, in particular, allows high speed and precise printing of cells into any bioink and with high viability. In this study, we use laser bioprinting to engineer urinary bladder tissue for regenerative medicine applications. Using a natural hydrogel and primary smooth muscle cells and urothelial cells, we have managed to print ex vivo bladder explants which recapitulate the structure of native urinary bladder.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Panagiotis Karakaidos, Zoi Kanaki, Stavroula Elezoglou, Chrysoula Chandrinou, Yiannis Ntounias, Teresa Franchi-Mendes, Ana T. Rufino, Fabiana Pereira, Ana Fernandes-Platzgummer, Cláudia Lobato da Silva, Catarina A. Custodio, Ioanna Zergioti, and Apostolos Klinakis "Laser bioprinting for engineering urinary bladder tissue", Proc. SPIE 12817, Advanced Photonics in Urology 2024, 1281704 (13 March 2024); https://doi.org/10.1117/12.3001512
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KEYWORDS
Bladder

Bioprinting

Engineering

Nervous system

Printing

Explants

Regenerative medicine

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