Low-level luminescence as a method of detecting the UV influence on biological systems

Wei-Ping Mei; Fritz Albert Popp

doi:10.1117/12.201246

10 February 1995 Low-level luminescence as a method of detecting the UV influence on biological systems

Wei-Ping Mei, Fritz Albert Popp

Proceedings Volume 2331, Medical Sensors II and Fiber Optic Sensors; (1995) https://doi.org/10.1117/12.201246
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

It is well known that low-level luminescence is correlated to many physiological and biological parameters, e.g. cell cycle, temperature, oxidation- and UV-stress. We report some new approaches on low-level luminescence measurements and UV influence on different biological systems. One example concerns yeast cultures, which show an increasing intensity of luminescence after UV-treatment with a maximum after 1.5 h. Investigations on normal human fibroblasts and keratinocytes display different longtime kinetics: The former show no changes of the luminescence in time, the latter an increase that reaches the maximum after 9 h. The time-dependent spectral measurement on xeroderma pigmentosum after UV-treatment displays a time-shift of the action-spectra shifting the maximum from 400 nm to 420 nm in 12 h. Some results on neutrophils reveals spectral UV influence on respiratory burst and the cellular repair system. The results on human skin display spectral changes of low-level luminescence after UV-treatment. These results provide a useful tool of analyzing UV influence on human skin.

Citation Download Citation

Wei-Ping Mei and Fritz Albert Popp "Low-level luminescence as a method of detecting the UV influence on biological systems", Proc. SPIE 2331, Medical Sensors II and Fiber Optic Sensors, (10 February 1995); https://doi.org/10.1117/12.201246

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