Paper
31 January 1996 Measurements of light penetration into human tissues in vivo
Vladimir Iani, Johan Moan, Li Wei Ma
Author Affiliations +
Abstract
A main factor to consider before photochemotherapy (PCT) is chosen to treat a tumor is whether sufficient fluences of light can reach the base of the tumor. The choice of optimal wavelengths for PCT should also be based on a knowledge of the optical penetration spectrum of the tumor. By means of a fiberoptic probe, adapted to a commercial fluorescence spectrometer, it is possible to measure the penetration depths of visible light into living, human tissues. We have performed such experiments, using the light from a 1000 W Xenon lamp. The light was guided from the lamp to the tissue by a perspex rod and the fluence rate penetrating different thickness of tissue was monitored by the fiberoptic probe. From penetration curves obtained at a number of wavelengths, it was possible to construct an accurate optical penetration spectrum of the tissue.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Vladimir Iani, Johan Moan, and Li Wei Ma "Measurements of light penetration into human tissues in vivo", Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); https://doi.org/10.1117/12.230985
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Cited by 6 scholarly publications.
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KEYWORDS
Tissues

In vivo imaging

Tissue optics

Tumors

Lamps

Absorption

Fiber optics

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