Clinical effectiveness of low-power laser radiation and functioning of hemosalivatory barrier in patients with rheumatic diseases

Natalia D. Gladkova; Alexander B. Karachistov; Lia G. Komarova; Olga P. Alekseeva; Elena A. Grunina

doi:10.1117/12.259988

25 November 1996 Clinical effectiveness of low-power laser radiation and functioning of hemosalivatory barrier in patients with rheumatic diseases

Natalia D. Gladkova, Alexander B. Karachistov, Lia G. Komarova, Olga P. Alekseeva, Elena A. Grunina

Author Affiliations +

Proceedings Volume 2929, Effects of Low-Power Light on Biological Systems II; (1996) https://doi.org/10.1117/12.259988
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

We have estimated the clinical effectiveness of several regimes and ways of low power laser therapy (LT) on the basis of a double 'blind', placebo-controlling randomizing comparative test in 454 patients with rheumatic diseases (RD). LT for RD has a well-expressed placebo effect. The level of clinical effect of LT for RD is not so high. We couldn't achieve 'a considerable improvement' in any cases, 'an improvement' was secured in only 18 percent. LT should be viewed as a symptomatic means, with a primary anesthetic and feebly expressed anti-inflammatory effect, which can not influence the course of the rheumatoid process. Only in 15 percent of patients with RD, a sufficient functioning of hemo-salivary barrier was observed, the latter providing a reserve for adaption mechanism, which leads under the influence of stressor agents of medium strength not only to anesthetic, but also to moderately expressed anti- inflammatory effect.

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Natalia D. Gladkova, Alexander B. Karachistov, Lia G. Komarova, Olga P. Alekseeva, and Elena A. Grunina "Clinical effectiveness of low-power laser radiation and functioning of hemosalivatory barrier in patients with rheumatic diseases", Proc. SPIE 2929, Effects of Low-Power Light on Biological Systems II, (25 November 1996); https://doi.org/10.1117/12.259988

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