Operational experience of a large-area x-ray camera for protein crystallography

Istvan Naday; R. Sanishvili; A. Joachimiak; Edwin M. Westbrook; Anthony R. Jorden; Paul W. Loeffen

doi:10.1117/12.367124

6 October 1999 Operational experience of a large-area x-ray camera for protein crystallography

Istvan Naday, R. Sanishvili, A. Joachimiak, Edwin M. Westbrook, Anthony R. Jorden, Paul W. Loeffen

Proceedings Volume 3774, Detectors for Crystallography and Diffraction Studies at Synchrotron Sources; (1999) https://doi.org/10.1117/12.367124
Event: SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, 1999, Denver, CO, United States

Abstract

After 3 years experience of operating very large area (210 mm X 210 mm) CCD-based detectors at the Advanced Photon Source, operational experience is reported. Four such detectors have been built, two for Structural Biology Center (APS-1 and SBC-2), one for Basic Energy Sciences Synchrotron Radiation Center (Gold-2) at Argonne National Laboratory's Advanced Photon Source and one for Osaka University by Oxford Instruments, for use at Spring 8 (PX-210). The detector is specifically designed as a high resolution and fast readout camera for macromolecular crystallography. Design trade-offs for speed and size are reviewed in light of operational experience and future requirements are considered. Operational data and examples of crystallography data are presented, together with plans for future development.

Citation Download Citation

Istvan Naday, R. Sanishvili, A. Joachimiak, Edwin M. Westbrook, Anthony R. Jorden, and Paul W. Loeffen "Operational experience of a large-area x-ray camera for protein crystallography", Proc. SPIE 3774, Detectors for Crystallography and Diffraction Studies at Synchrotron Sources, (6 October 1999); https://doi.org/10.1117/12.367124

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KEYWORDS

Sensors

Charge-coupled devices

Diffraction

X-rays

Crystallography

Crystals

Proteins

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