Modeling of a tapered tubular optical waveguide probe for fluorescent immunosensors

He Cao; Arthur Garth Rand; Stephen V. Letcher

doi:10.1117/12.385542

9 May 2000 Modeling of a tapered tubular optical waveguide probe for fluorescent immunosensors

He Cao, Arthur Garth Rand, Stephen V. Letcher

Proceedings Volume 4077, International Conference on Sensors and Control Techniques (ICSC 2000); (2000) https://doi.org/10.1117/12.385542
Event: International Conference on Sensors and Control Techniques (ICSC2000), 2000, Wuhan, China

Abstract

A tubular optical probe for fluorescent immunosensors based on magnetic focusing of paramagnetic microspheres has been developed. The optical probe features a tubular optical waveguide tapered at both ends with a tapered magnet embedded inside the waveguide. Laser light is delivered to a dye-labeled spot in the inner surface of a cuvette and the fluorescent signal is guided to an optical detection system. A 3D computer model of this system has been created and its optical properties evaluated with a commercially available non-sequential ray-trace program. Up to 10,000 rays are traced from the laser to the cuvette and again from the fluorescent source to the detector. Results lead to the optimization of the component properties.

Citation Download Citation

He Cao, Arthur Garth Rand, and Stephen V. Letcher "Modeling of a tapered tubular optical waveguide probe for fluorescent immunosensors", Proc. SPIE 4077, International Conference on Sensors and Control Techniques (ICSC 2000), (9 May 2000); https://doi.org/10.1117/12.385542

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available