Preliminary tests on a new near-infrared continuous-wave tissue oximeter

Claudia Casavola; Giuseppe Cicco; Anna Pirrelli; Pietro Mario Lugara

doi:10.1117/12.407618

22 November 2000 Preliminary tests on a new near-infrared continuous-wave tissue oximeter

Claudia Casavola, Giuseppe Cicco, Anna Pirrelli, Pietro Mario Lugara

Proceedings Volume 4160, Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment; (2000) https://doi.org/10.1117/12.407618
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

We present a preliminary study, in vitro and in vivo, with a novel device for near-infrared tissue oximetry. The light sources used are two quasi-continuous-wave LEDs, emitting at 656 and 851 nm, and the detector is a photodiode. The data are acquired in back-scattering configuration, thus allowing the non-invasive characterization of thick tissues. Stability tests were performed by placing the optical probe on a tissue- like phantom and acquiring data for periods of time ranging from 5 to 40 minutes. No significant drifts in the DC signal were observed after a warm-up period of no more than 10 minutes. We performed reproducibility tests by repositioning the optical probe on the phantom for a number of times. We found a reproducibility better than 5% in the DC signal. We also present the results of a preliminary study conducted in vivo, on the calf muscle of human subjects. We report a comparison of the results obtained with the near-infrared oximeter with the values of blood oxygenation ctO₂ measured with conventional chemical tests.

Citation Download Citation

Claudia Casavola, Giuseppe Cicco, Anna Pirrelli, and Pietro Mario Lugara "Preliminary tests on a new near-infrared continuous-wave tissue oximeter", Proc. SPIE 4160, Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment, (22 November 2000); https://doi.org/10.1117/12.407618

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