Optical manipulation of microscopic particles and biological cells by laser microbeams

Yan Li; Jinghua Liu; Xiangwang Meng; Shulian Zhang; Zhicheng Zhang

doi:10.1117/12.482980

12 September 2002 Optical manipulation of microscopic particles and biological cells by laser microbeams

Yan Li, Jinghua Liu, Xiangwang Meng, Shulian Zhang, Zhicheng Zhang

Proceedings Volume 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment; (2002) https://doi.org/10.1117/12.482980
Event: Photonics Asia, 2002, Shanghai, China

Abstract

The paper introduces to construct a laser micro-beam system for cell manipulation. This system consists of an optical tweezers with optical kinetic effect, and an optical scissor, which is a Nd:YAG laser beam with synthetical effect of sound pressure, thermal expansion and bounce-back pressure. The system can manipulate, deflect, rotate, and punch cells, and so on after we couple two laser beams into microscope. We construct a laser micro-beam system and gained anticipated experiment results. We can successfully manipulate cells in suspension, concise chromosome and punch a hole in cells or organelles on the basis of the system.

Citation Download Citation

Yan Li, Jinghua Liu, Xiangwang Meng, Shulian Zhang, and Zhicheng Zhang "Optical manipulation of microscopic particles and biological cells by laser microbeams", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); https://doi.org/10.1117/12.482980

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