Influence of changes in optical pathway on efficiency of light transmission through tissues

Anna Cysewska-Sobusiak; Z. Krawieki

doi:10.1117/12.509706

1 April 2003 Influence of changes in optical pathway on efficiency of light transmission through tissues

Anna Cysewska-Sobusiak, Z. Krawieki

Proceedings Volume 5064, Lightmetry 2002: Metrology and Testing Techniques Using Light; (2003) https://doi.org/10.1117/12.509706
Event: Lightmetry 2002, 2002, Warsaw, Poland

Abstract

The subject of this paper is concerned with analysis of bio-optical signals to be acquired from a tissue slab exposed to selective transillumination. Changes in biophysical and optical parameters of the layered living tissue composition are considered to predict output results of occurring interactions. Especially, influence of changes in optical pathway on efficiency of light transmission through tissues is considered. Series of computer-aided simulation for a representative tissue set have been performed. On the background of data reported in the literature, the authors of this paper describe results collected by them during comparative analytical as well as experimental studies. Taking into account the 3-D approach to the object modeling, it was assumed that dimensions of the smallest component in the object structure are 10 μm x 10 μm x 10 μm. All layers were divided into such elementary cubes. During more than 100,000 simulations in a given direction, the effects of increase in the optical pathway were studied. Exemplary results of calculations for the transilluminated tissue slab are presented, at red light to be acting. The results are presented graphically, where specific changes in the transmittance intensity are given against the thickness of a given layer, which should be treated either optically thin or thick.

Citation Download Citation

Anna Cysewska-Sobusiak and Z. Krawieki "Influence of changes in optical pathway on efficiency of light transmission through tissues", Proc. SPIE 5064, Lightmetry 2002: Metrology and Testing Techniques Using Light, (1 April 2003); https://doi.org/10.1117/12.509706

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