Janelle M Reyes-Goddard,1,2 Anthony C Woodman,1,3 Nicholas Stone,1,2 Hugh Barr,1,2 John Alan Creighton,4 Yuika Saito,5 David Batchelder5
1Cranfield Univ. (United Kingdom) 2Gloucestershire Royal Hospital (United Kingdom) 3Gloucestershire Royal Hospital (United Kingdom) 4Univ. of Kent (United Kingdom) 5Univ. of Leeds (United Kingdom)
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When human tear film’s constituents are identified, it is diagnostically useful. Surface enhanced Raman scattering (SERS) can quickly measure, the components at their low concentrations. Reproducible spectra were collected from evaporated gold thin film and silver mirror reaction glass substrates. Synthetic tears were measured on optimised substrates as proof of principle. Further analysis was used to discriminate between diseased and normal tears.
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Janelle M Reyes-Goddard, Anthony C Woodman, Nicholas Stone, Hugh Barr, John Alan Creighton, Yuika Saito, David Batchelder, "Surface-enhanced Raman scattering of the tear film," Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); https://doi.org/10.1117/12.500643