Fast orthogonal search method for modeling nonlinear hemodynamic response in fMRI

Xingfeng Li; Jie Tian; Xiaoxiang Wang; Jianping Dai; Lin Ai

doi:10.1117/12.536165

30 April 2004 Fast orthogonal search method for modeling nonlinear hemodynamic response in fMRI

Xingfeng Li, Jie Tian, Xiaoxiang Wang, Jianping Dai, Lin Ai

Proceedings Volume 5369, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images; (2004) https://doi.org/10.1117/12.536165
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

This study presents a fast orthogonal search (FOS) method for modeling fMRI time series. Based on the system identification theory, an orthogonalization procedure to model the fMRI time series is described. FOS method does not require equally space data, and can resolve sinusoidal frequencies much more closely than Fourier transform method. After the time series are modeled by means of the FOS, F-test is employed to detect the activation regions. Eight volunteers' data were collected to validate the proposed method. The results demonstrate the feasibility of the proposed method.

Citation Download Citation

Xingfeng Li, Jie Tian, Xiaoxiang Wang, Jianping Dai, and Lin Ai "Fast orthogonal search method for modeling nonlinear hemodynamic response in fMRI", Proc. SPIE 5369, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, (30 April 2004); https://doi.org/10.1117/12.536165

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