In vivo imaging with high-speed full-range complex spectral domain optical coherence tomography

Erich Goetzinger; Michael Pircher; Rainer Andreas Leitgeb; Adolf Friedrich Fercher; Christoph K. Hitzenberger

doi:10.1117/12.592763

13 April 2005 In vivo imaging with high-speed full-range complex spectral domain optical coherence tomography

Erich Goetzinger, Michael Pircher, Rainer Andreas Leitgeb, Adolf Friedrich Fercher, Christoph K. Hitzenberger

Proceedings Volume 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX; (2005) https://doi.org/10.1117/12.592763
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

We present a high-speed full range complex spectral optical coherence tomography system, which achieves an A-scan rate of 20000 depth profiles per second. By inserting a phase modulator into the reference arm and recording of every other spectrum with a 90∞phase shift (introduced by the phase modulator) we are able to distinguish between negative and positive optical path differences. A modified two-frame algorithm eliminates the problem of suppressing symmetric structure terms in the final image. To demonstrate the performance of our system we present images of the human anterior chamber in vivo.

Citation Download Citation

Erich Goetzinger, Michael Pircher, Rainer Andreas Leitgeb, Adolf Friedrich Fercher, and Christoph K. Hitzenberger "In vivo imaging with high-speed full-range complex spectral domain optical coherence tomography", Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, (13 April 2005); https://doi.org/10.1117/12.592763

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KEYWORDS

Mirrors

Fourier transforms

In vivo imaging

Modulators

Optical coherence tomography

Phase shifts

Electro optics

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