Doppler spectroscopy of blood in capillary plexus under the action of 40% glucose solution

A. N. Korolevich; A. Yelshin; M. Belsley; M. Mota

doi:10.1117/12.696961

21 July 2006 Doppler spectroscopy of blood in capillary plexus under the action of 40% glucose solution

A. N. Korolevich, A. Yelshin, M. Belsley, M. Mota

Proceedings Volume 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII; 61630I (2006) https://doi.org/10.1117/12.696961
Event: Saratov Fall Meeting 2005, 2005, Saratov, Russian Federation

Abstract

The investigation of blood dynamical characteristics in the skin under the action of 40% glucose solution was performed in vivo by the laser Doppler technique. Experiments demonstrate that glucose solution affects significantly the blood perfusion and concentration. Qualitative explanation was made for observed perfusion dynamic effect in the skin dermis based on the following factors: tissue cells shrinkage and additional capillaries opening under osmotic stress. The size of glucose vesicle lens was measured under the skin by ultrasonography. The analysis of vesicle sizes monitoring leads to the conclusion that glucose lens spread, basically, along the skin than in the perpendicular to the skin surface direction. Obtained results show the significant anisotropic perturbation of the dynamic characteristics of blood in vascular plexus under the optical active solution influence that must be taken into consideration during optical clarification of biological tissues.

Citation Download Citation

A. N. Korolevich, A. Yelshin, M. Belsley, and M. Mota "Doppler spectroscopy of blood in capillary plexus under the action of 40% glucose solution", Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61630I (21 July 2006); https://doi.org/10.1117/12.696961

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