Raman spectroscopic characterization on cervical neoplasm in biopsy direction

Hsiao Hsin Shin; Yan Sheng Tsai; Tao Yuan Wang; Shou Chia Chu; Huihua Kenny Chiang

doi:10.1117/12.700050

6 February 2007 Raman spectroscopic characterization on cervical neoplasm in biopsy direction

Hsiao Hsin Shin, Yan Sheng Tsai, Tao Yuan Wang, Shou Chia Chu, Huihua Kenny Chiang

Proceedings Volume 6430, Advanced Biomedical and Clinical Diagnostic Systems V; 643019 (2007) https://doi.org/10.1117/12.700050
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Raman spectroscopy was applied to distinguish the spectroscopic information between normal cervical tissues (14) and cervical neoplasia (17), including low grade squamous intraepithelial lesions (6) and high grade squamous intraepithelial lesions (11). Standard pathological sections of these cervical tissues were measured from superficial to stroma layers. We have normalized significant Raman peaks, 1250 and 1579-1656 cm^-1 by taking a ratio over a stationary Raman at 1004 cm^-1, and successfully discriminated between normal and neoplasm cervical tissues.

Citation Download Citation

Hsiao Hsin Shin, Yan Sheng Tsai, Tao Yuan Wang, Shou Chia Chu, and Huihua Kenny Chiang "Raman spectroscopic characterization on cervical neoplasm in biopsy direction", Proc. SPIE 6430, Advanced Biomedical and Clinical Diagnostic Systems V, 643019 (6 February 2007); https://doi.org/10.1117/12.700050

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available