Development of a fully 3D system model in iterative expectation-maximization reconstruction for cone-beam SPECT

Hongwei Ye; Levon Vogelsang; David H. Feiglin; Edward D. Lipson; Andrzej Krol

doi:10.1117/12.772659

18 March 2008 Development of a fully 3D system model in iterative expectation-maximization reconstruction for cone-beam SPECT

Hongwei Ye, Levon Vogelsang, David H. Feiglin, Edward D. Lipson, Andrzej Krol

Author Affiliations +

Proceedings Volume 6913, Medical Imaging 2008: Physics of Medical Imaging; 69132K (2008) https://doi.org/10.1117/12.772659
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

In order to improve reconstructed image quality for cone-beam collimator SPECT, we have developed and implemented a fully 3D reconstruction, using an ordered subsets expectation maximization (OSEM) algorithm, along with a volumetric system model - cone-volume system model (CVSM), a modified attenuation compensation, and a 3D depth- and angle-dependent resolution and sensitivity correction. SPECT data were acquired in a 128×128 matrix, in 120 views with a single circular orbit. Two sets of numerical Defrise phantoms were used to simulate CBC SPECT scans, and low noise and scatter-free projection datasets were obtained using the SimSET Monte Carlo package. The reconstructed images, obtained using OSEM with a line-length system model (LLSM) and a 3D Gaussian post-filter, and OSEM with FVSM and a 3D Gaussian post-filter were quantitatively studied. Overall improvement in the image quality has been observed, including better transaxial resolution, higher contrast-to-noise ratio between hot and cold disks, and better accuracy and lower bias in OSEM-CVSM, compared with OSEM-LLSM.

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Hongwei Ye, Levon Vogelsang, David H. Feiglin, Edward D. Lipson, and Andrzej Krol "Development of a fully 3D system model in iterative expectation-maximization reconstruction for cone-beam SPECT", Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69132K (18 March 2008); https://doi.org/10.1117/12.772659

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KEYWORDS

3D modeling

Systems modeling

Single photon emission computed tomography

Collimators

Reconstruction algorithms

Image quality

3D image reconstruction

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