First Observation Of The Wavelength-Dependent Photoproduction Of The 4E,15Z Configurational Isomer Of Bilirubin Bound To Human Serum Albumin

Antony F. Mc Donagh; Giovanni Agati; Franco Fusi; R. Pratesi

doi:10.1117/12.937088

10 July 1987 First Observation Of The Wavelength-Dependent Photoproduction Of The 4E,15Z Configurational Isomer Of Bilirubin Bound To Human Serum Albumin

Antony F. Mc Donagh, Giovanni Agati, Franco Fusi, R. Pratesi

Author Affiliations +

Proceedings Volume 0701, 1986 European Conf on Optics, Optical Systems and Applications; (1987) https://doi.org/10.1117/12.937088
Event: 1986 International European Conference on Optics, Optical Systems, and Applications, 1986, Florence, Italy

Abstract

The photochemistry of bilirubin (BR) is of considerable interest because of its importance in the treatment of neonatal jaundice with visible light phototherapy. Patients are irradiated with blue, white or green fluorescent lamps to induce conversion of the unexcretable and toxic bilirubin to more polar, water-soluble and easily excreted photoproducts. The molecular mechanisms responsible for the phototherapeutic action of light on jaundiced babies have not jet been completely elucidated.

Citation Download Citation

Antony F. Mc Donagh, Giovanni Agati, Franco Fusi, and R. Pratesi "First Observation Of The Wavelength-Dependent Photoproduction Of The 4E,15Z Configurational Isomer Of Bilirubin Bound To Human Serum Albumin", Proc. SPIE 0701, 1986 European Conf on Optics, Optical Systems and Applications, (10 July 1987); https://doi.org/10.1117/12.937088

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