A new nano-structured SPR sensor was devised to improve its sensitivity. Nano-scaled silica particles were used as the
template to fabricate nano-structure. The surface of the silica particles was modified with thiol group and a single layer
of the modified silica particles was attached on the gold or silver thin film using Langmuir-Blodgett (LB) method.
Thereafter, gold or silver was coated on the template by an e-beam evaporator. Finally, the nano-structured surface with
basin-like shape was obtained after removing the silica particles by sonication. Applying the new developed SPR sensor
to a model food of alcoholic beverage, the sensitivities for the gold and silver nano-structured sensors, respectively, had
95% and 126% higher than the conventional one.
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