In vivo bi-directional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities

Rene M. Werkmeister; Nikolaus Dragostinoff; Michael Pircher; Erich Götzinger; Christoph K. Hitzenberger; Rainer A. Leitgeb; Leopold Schmetterer

doi:10.1117/12.809382

24 February 2009 In vivo bi-directional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities

Rene M. Werkmeister, Nikolaus Dragostinoff, Michael Pircher, Erich Götzinger, Christoph K. Hitzenberger, Rainer A. Leitgeb, Leopold Schmetterer

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Proceedings Volume 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII; 71681P (2009) https://doi.org/10.1117/12.809382
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

A bidirectional FDOCT system capable of measuring absolute velocities of moving scatterers is described. In this setup the sample is illuminated with two differently polarized beams. These two probe beams impinging onto the sample at a known angle. The velocity estimation is independent of the exact direction of the velocity vector in the detection plane. Evaluation measurements were performed on a rotating disc driven at well defined velocities and tilted by various small angles around to π/2. Our results indicate a high correlation between pre-set and estimated velocities and the independency of these velocities from the tilting angle of the disc. Additional preliminary in vivo measurements proof the ability of this new method to measure absolute blood flow velocities in human retinal vessels.

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Rene M. Werkmeister, Nikolaus Dragostinoff, Michael Pircher, Erich Götzinger, Christoph K. Hitzenberger, Rainer A. Leitgeb, and Leopold Schmetterer "In vivo bi-directional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities", Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71681P (24 February 2009); https://doi.org/10.1117/12.809382

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KEYWORDS

Velocity measurements

In vivo imaging

Doppler tomography

Optical coherence tomography

Polarization

Laser beam diagnostics

Wave plates

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