3D visualization of tissue microstructures using optical coherence tomography needle probes

Rodney W. Kirk; Robert A. McLaughlin; Bryden C. Quirk; Andrea Curatolo; David D. Sampson

doi:10.1117/12.887366

17 May 2011 3D visualization of tissue microstructures using optical coherence tomography needle probes

Rodney W. Kirk, Robert A. McLaughlin, Bryden C. Quirk, Andrea Curatolo, David D. Sampson

Proceedings Volume 7753, 21st International Conference on Optical Fiber Sensors; 77536W (2011) https://doi.org/10.1117/12.887366
Event: 21st International Conference on Optical Fibre Sensors (OFS21), 2011, Ottawa, Canada

Abstract

Optical coherence tomography (OCT) needle probes use miniaturized focusing optics encased in a hypodermic needle. Needle probes can scan areas of the body that are too deep to be imaged by other OCT systems. This paper presents an OCT needle probe-based system that is capable of acquiring three-dimensional scans of tissue structures. The needle can be guided to a target area and scans acquired by rotating and pulling-back the probe. The system is demonstrated using ex vivo human lymph node and sheep lung samples. Multiplanar reconstructions are shown of both samples, as well as the first published 3D volume rendering of lung tissue acquired with an OCT needle probe.

Citation Download Citation

Rodney W. Kirk, Robert A. McLaughlin, Bryden C. Quirk, Andrea Curatolo, and David D. Sampson "3D visualization of tissue microstructures using optical coherence tomography needle probes", Proc. SPIE 7753, 21st International Conference on Optical Fiber Sensors, 77536W (17 May 2011); https://doi.org/10.1117/12.887366

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available