All fiber 1064-nm time-lens source for coherent anti-Stokes Raman scattering and stimulated Raman scattering microscopy

Ke Wang; Christian W. Freudiger; Jennifer H. Lee; Brian G. Saar; X. Sunney Xie; Chris Xu

doi:10.1117/12.875898

11 February 2011 All fiber 1064-nm time-lens source for coherent anti-Stokes Raman scattering and stimulated Raman scattering microscopy

Ke Wang, Christian W. Freudiger, Jennifer H. Lee, Brian G. Saar, X. Sunney Xie, Chris Xu

Author Affiliations +

Proceedings Volume 7903, Multiphoton Microscopy in the Biomedical Sciences XI; 79030X (2011) https://doi.org/10.1117/12.875898
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We use the time-lens concept to demonstrate a new scheme for synchronization of two pulsed light sources for biological imaging. An all fiber, 1064 nm time-lens source is synchronized to a picosecond solid-state Ti: Sapphire mode-locked laser by using the mode-locked laser pulses as the clock. We demonstrate the application of this synchronized source for CARS and SRS imaging by imaging mouse tissues. Synchronized two wavelength pulsed source is a major technical difficulty for CARS and SRS imaging. The time-lens source demonstrated here may provide an all-fiber, user friendly alternative for future SRS imaging.

Citation Download Citation

Ke Wang, Christian W. Freudiger, Jennifer H. Lee, Brian G. Saar, X. Sunney Xie, and Chris Xu "All fiber 1064-nm time-lens source for coherent anti-Stokes Raman scattering and stimulated Raman scattering microscopy", Proc. SPIE 7903, Multiphoton Microscopy in the Biomedical Sciences XI, 79030X (11 February 2011); https://doi.org/10.1117/12.875898

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