Synthesis of hybrid organic-inorganic near-IR responsive magnetic nanoparticles for cancer theragnosis

Doyeon Bang; Taeksu Lee; Jihye Choi; Joseph Park; Byunghoon Kang; Yong-Min Huh; Seungjoo Haam

doi:10.1117/12.2001814

24 October 2012 Synthesis of hybrid organic-inorganic near-IR responsive magnetic nanoparticles for cancer theragnosis

Doyeon Bang, Taeksu Lee, Jihye Choi, Joseph Park, Byunghoon Kang, Yong-Min Huh, Seungjoo Haam

Proceedings Volume 8548, Nanosystems in Engineering and Medicine; 85484G (2012) https://doi.org/10.1117/12.2001814
Event: SPIE Nanosystems in Engineering + Medicine, 2012, Incheon, Korea, Republic of

Abstract

Hybrid organic-inorganic near-infrared responsive magnetic nanoparticles were synthesized for theragnosis combined with localized therapy. In detail, inorganic super-paramagnetic nanoparticles were embedded inside organic polyaniline matrix, which enables localized photothermal therapy upon NIR illumination under intracellular acidic/oxidative condition. In this structure, super-paramagnetic nanoparticle works as MRI contrast agent, that enables the visualization of a tumor and polyaniline works for near-infrared responsive tumor ablation.

Citation Download Citation

Doyeon Bang, Taeksu Lee, Jihye Choi, Joseph Park, Byunghoon Kang, Yong-Min Huh, and Seungjoo Haam "Synthesis of hybrid organic-inorganic near-IR responsive magnetic nanoparticles for cancer theragnosis", Proc. SPIE 8548, Nanosystems in Engineering and Medicine, 85484G (24 October 2012); https://doi.org/10.1117/12.2001814

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