A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Christopher J. Fong; Molly Flexman; Jennifer W. Hoi; Lauren Geller; Maria Garzon; Hyun K. Kim; Andreas H. Hielscher

doi:10.1117/12.2004717

25 March 2013 A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Christopher J. Fong, Molly Flexman, Jennifer W. Hoi, Lauren Geller, Maria Garzon, Hyun K. Kim, Andreas H. Hielscher

Proceedings Volume 8578, Optical Tomography and Spectroscopy of Tissue X; 85780R (2013) https://doi.org/10.1117/12.2004717
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Infantile hemangiomas (IH) are common vascular growths that occur in 5-10% of neonates and have the potential to cause disfiguring and even life-threatening complications. With no objective tool to monitor IH, a handheld wireless device (HWD) that uses diffuse optical spectroscopy has been developed for use in assessment of IH by measurements in absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Reconstructions of these variables can be computed using a multispectral evolution algorithm. We validated the new system by experimental studies using phantom experiments and a clinical study is under way to assess the utility of DOI for IH.

Citation Download Citation

Christopher J. Fong, Molly Flexman, Jennifer W. Hoi, Lauren Geller, Maria Garzon, Hyun K. Kim, and Andreas H. Hielscher "A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas ", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85780R (25 March 2013); https://doi.org/10.1117/12.2004717

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KEYWORDS

Scattering

Absorption

Tissue optics

Tissues

Chromophores

Optical spectroscopy

Sensors

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