Low-frequency dynamics of proteins and aqueous solutions studied by terahertz time-domain spectroscopy

Naoki Yamamoto; Akané Ishihara; Azusa Kaneko; Haruka Iguchi; Ohki Kambara; Atsuo Tamura; Keisuke Tominaga

doi:10.1117/12.2007253

14 March 2013 Low-frequency dynamics of proteins and aqueous solutions studied by terahertz time-domain spectroscopy

Naoki Yamamoto, Akané Ishihara, Azusa Kaneko, Haruka Iguchi, Ohki Kambara, Atsuo Tamura, Keisuke Tominaga

Proceedings Volume 8623, Ultrafast Phenomena and Nanophotonics XVII; 862306 (2013) https://doi.org/10.1117/12.2007253
Event: SPIE OPTO, 2013, San Francisco, California, United States

Abstract

We studied low-frequency spectra of hydration water molecules around the hydrophobic probe in an aqueous solution by using tetraalkylammonium cation as a probe and terahertz time-domain spectroscopic technique. The phenomenon, called dynamical transition, has been known to be universally observed among proteins and polypeptides. In this work we investigated temperature and hydration dependence of low-frequency dynamics to clarify relationships between the dynamical transition and protein structures, and its functional states. We also mention general behaviors of the lowfrequency spectra of globular proteins.

Citation Download Citation

Naoki Yamamoto, Akané Ishihara, Azusa Kaneko, Haruka Iguchi, Ohki Kambara, Atsuo Tamura, and Keisuke Tominaga "Low-frequency dynamics of proteins and aqueous solutions studied by terahertz time-domain spectroscopy", Proc. SPIE 8623, Ultrafast Phenomena and Nanophotonics XVII, 862306 (14 March 2013); https://doi.org/10.1117/12.2007253

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