Paper
29 May 2013 Generalized mathematical-computational-electronic model of MPTP- induced Parkinsonism
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Abstract
The substance 1–methyl–4–phenyl–1, 2, 3, 6 tetrahy dropyridine (MPTP) has been studied as a major cause of neurodegeneration dopaminica, which is specifically related to Parkinson's disease. The analysis is in terms of the diffusion of the substance to the mammalian brain, by evaluating the diffusion equation in a spherical coordinate system, being η (collective diffusion term) spatially modulated. Although the progress of the disease with respect to time has not been established with certainty, an attempt to find a stable pattern of the concentration of MPTP and its effects has been made.
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Daniela Jaramillo Raquejo "Generalized mathematical-computational-electronic model of MPTP- induced Parkinsonism", Proc. SPIE 8723, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring III, 87231G (29 May 2013); https://doi.org/10.1117/12.2014331
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KEYWORDS
Brain

Neurons

Mathematical modeling

Diffusion

Parkinson's disease

Visualization

Spherical lenses

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