Analysis of retinal nerve fiber tissue deformation in-vivo using temporal phase contrast OCT

Sylvia Desissaire; Florian Schwarzhans; Stefan Steiner; Clemens Vass; Georg Fischer; Michael Pircher; Christoph K. Hitzenberger

doi:10.1117/12.2611520

7 March 2022 Analysis of retinal nerve fiber tissue deformation in-vivo using temporal phase contrast OCT

Sylvia Desissaire, Florian Schwarzhans, Stefan Steiner, Clemens Vass, Georg Fischer, Michael Pircher, Christoph K. Hitzenberger

Author Affiliations +

Proceedings Volume PC11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI; PC119480H (2022) https://doi.org/10.1117/12.2611520
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

We introduce a new method, temporal phase contrast (TPC) OCT, to measure sub-micron tissue motion in-vivo in the retina over an extended timeframe, i.e. over several seconds. The analysis is based on the calculation of the phase differences between an initial reference B-scan and each of the subsequent B-scans. In this study, retinal nerve fiber (RNF) tissue deformations induced by retinal vessels pulsating with the heartbeat were investigated in healthy volunteers. We show reproducible results of tissue expansion enabling to quantify the extent of the deformation and access the delay between expansion near the arteries and the veins.

Conference Presentation

Citation Download Citation

Sylvia Desissaire, Florian Schwarzhans, Stefan Steiner, Clemens Vass, Georg Fischer, Michael Pircher, and Christoph K. Hitzenberger "Analysis of retinal nerve fiber tissue deformation in-vivo using temporal phase contrast OCT", Proc. SPIE PC11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, PC119480H (7 March 2022); https://doi.org/10.1117/12.2611520

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available