Modelling the experimental and fundamental signal-to-noise in speckle contrast optical tomography

Lisa Kobayashi Frisk; Manish Verma; Chen-Hao P. Lin; Sumana Chetia; Faruk Beslija; Jason Trobaugh; Joseph P. Culver; Turgut Durduran

doi:10.1117/12.2610256

2 March 2022 Modelling the experimental and fundamental signal-to-noise in speckle contrast optical tomography

Lisa Kobayashi Frisk, Manish Verma, Chen-Hao P. Lin, Sumana Chetia, Faruk Beslija, Jason Trobaugh, Joseph P. Culver, Turgut Durduran

Author Affiliations +

Proceedings Volume PC11959, Dynamics and Fluctuations in Biomedical Photonics XIX; PC1195907 (2022) https://doi.org/10.1117/12.2610256
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

A variety of diffuse optical methods use laser speckle contrast and its statistics to non-invasively determine blood flow. In most cases, this implies very low detected count-rates which leads to systematic errors in determining the correct speckle statistics. We have developed a comprehensive method for simulating realistic speckle contrast resultant from light propagation in tissue taking into account experimental and fundamental sources of noise. Results of the simulation are used to determine the relationship of these parameters on the precision and accuracy of the speckle contrast signal.

Conference Presentation

Citation Download Citation

Lisa Kobayashi Frisk, Manish Verma, Chen-Hao P. Lin, Sumana Chetia, Faruk Beslija, Jason Trobaugh, Joseph P. Culver, and Turgut Durduran "Modelling the experimental and fundamental signal-to-noise in speckle contrast optical tomography", Proc. SPIE PC11959, Dynamics and Fluctuations in Biomedical Photonics XIX, PC1195907 (2 March 2022); https://doi.org/10.1117/12.2610256

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Speckle

Optical tomography

Cameras

Modeling

Signal to noise ratio

Device simulation

Sensors

Show All Keywords

Keywords/Phrases

Search In:

Publication Years