Presentation
7 March 2022 Photoacoustic imaging of 3D-printed vascular models
Author Affiliations +
Abstract
Understanding thrombosis formation is necessary for developing safe and effective treatments. We fabricated sophisticated in vitro models of blood vessels with internal microchannels by using digital light processing-based 3D printing method. Photoacoustic microscopy (PAM) offers a useful platform for imaging 3D-printed vascular structures with different patterns of microchannels. Our results show that PAM can provide clear microchannel structures at depths up to 3.6 mm. We further quantified the blood oxygenation in the 3D-printed vascular models, showing that thrombi had much lower oxygenation than the normal blood. Integration of PAM with 3D printing/bioprinting will enable numerous applications in tissue engineering.
Conference Presentation
© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chenshuo Ma, Wanlu Li, Daiwei Li, Maomao Chen, Mian Wang, Laiming Jiang, Luis Santiago Mille, Carlos Ezio Garciamendez, Qifa Zhou, Yu Shrike Zhang, and Junjie Yao "Photoacoustic imaging of 3D-printed vascular models", Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC119601W (7 March 2022); https://doi.org/10.1117/12.2608413
Advertisement
Advertisement
KEYWORDS
3D modeling

Photoacoustic imaging

Autoregressive models

3D printing

Blood

In vitro testing

Visual process modeling

Back to Top