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Optical coherence tomography offers the highest spatial resolution for clinical intravascular imaging. Optical coherence polarimetry additionally measures polarization effects that afford insight into the microstructure and physical orientation of collagen or smooth muscle cells and the scattering properties of lipid-rich plaques. We have been making progress with simplifying the integration of optical coherence polarimetry into existing clinical instruments, with using the polarization contrast to enable AI-based segmentation facilitating automated lesion analysis, and with compensating the polarization effects of the rotating catheter. These efforts will empower clinical investigations that expand on the findings from our initial clinical pilot trials.
Martin Villiger
"Intravascular optical coherence polarimetry", Proc. SPIE PC12355, Diagnostic and Therapeutic Applications of Light in Cardiology 2023, PC1235504 (17 March 2023); https://doi.org/10.1117/12.2661500
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Martin Villiger, "Intravascular optical coherence polarimetry," Proc. SPIE PC12355, Diagnostic and Therapeutic Applications of Light in Cardiology 2023, PC1235504 (17 March 2023); https://doi.org/10.1117/12.2661500