Presentation
17 March 2023 Blue light enhances antibiotic activity in multidrug-resistant bacteria
Leon G. Leanse, Carolina dos Anjos, Rox R. Anderson, David C. Hooper, Tianhong Dai
Author Affiliations +
Abstract
Antimicrobial resistance is significant concern to public health that negatively impacts the worldwide populace. With the increasing incidences of multidrug-resistant (MDR) pathogens, treatment of infections is becoming more difficult than ever before. In recent years, our team has been involved with the use of blue light (BL) for the treatment of infection. BL is a potent microbicide that can kill a multiplicity of pathogenic microbes. A concern, however, is that the effects of BL are short lived, when the light switches off, so do the antimicrobial effects.Therefore, we considered, that we could increase the longevity of microbicidal activity of BL via its concomitant application with antibiotics. In this study, we tested our hypothesis that aBL can enhance antibiotic activity in MDR bacteria.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Leon G. Leanse, Carolina dos Anjos, Rox R. Anderson, David C. Hooper, and Tianhong Dai "Blue light enhances antibiotic activity in multidrug-resistant bacteria", Proc. SPIE PC12358, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2023, PC123580A (17 March 2023); https://doi.org/10.1117/12.2655368
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KEYWORDS
Bacteria

Pathogens

Medicine

Microorganisms

Oxygen

Resistance

Switches

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