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In previous Monte Carlo (MC) studies of modeling Fourier-domain optical coherence tomography (FD-OCT), the results obtained at single wavelength are often used to reconstruct the image despite of FD-OCT’s broadband nature. Here, we propose a novel image simulator for full-wavelength MC simulation of FD-OCT based on Mie theory, which combines the inverse discrete Fourier transform (IDFT) with a probability distribution-based signal pre-processing to eliminate the excessive noises in image reconstruction via IDFT caused by missing certain wavelength’s signals in some scattering events. Compared with the conventional method, the proposed simulator is more accurate and could better preserve the wavelength-dependent features.
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Jianing Mao, Yuye Ling, Ping Xue, Yikai Su, Hongshan Liu, "A Monte Carlo-based full-wavelength image simulator of Fourier-domain optical coherence tomography," Proc. SPIE PC12377, Optical Interactions with Tissue and Cells XXXIV, PC1237705 (7 March 2023); https://doi.org/10.1117/12.2648124