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5 October 2023 Real time spatial light modulation for informed photostimulation of neuronal cells
Wolfgang Losert, Dulara de Zoysa
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Proceedings Volume PC12649, Optical Trapping and Optical Micromanipulation XX; PC126491B (2023) https://doi.org/10.1117/12.2682243
Event: SPIE Nanoscience + Engineering, 2023, San Diego, California, United States
Abstract
We have developed a software platform to provide real-time readout of neuronal activity and downstream analysis which enables informed real-time modulation of neuronal activity through photostimulation during image acquisition. The downstream analysis within the real-time loop is rapid enough (at 30Hz for 250 neurons) to operate at widely used image acquisition rates.
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Wolfgang Losert and Dulara de Zoysa "Real time spatial light modulation for informed photostimulation of neuronal cells", Proc. SPIE PC12649, Optical Trapping and Optical Micromanipulation XX, PC126491B (5 October 2023); https://doi.org/10.1117/12.2682243
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KEYWORDS
Photostimulation
Spatial light modulators
Modulation
Neurons
Optical vortices
Holography
Image acquisition
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