Imaging and mapping local neuroanatomy surrounding a deep brain polarization-sensitive OCT catheter

Shadi Masoumi; Georgia Jones; Mireille Quemener; Martin Parent; Martin Villiger; Daniel Cote; Maxina Sheft

doi:10.1117/12.3005514

13 March 2024 Imaging and mapping local neuroanatomy surrounding a deep brain polarization-sensitive OCT catheter

Shadi Masoumi, Georgia Jones, Mireille Quemener, Martin Parent, Martin Villiger, Daniel Cote, Maxina Sheft

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC128302H (2024) https://doi.org/10.1117/12.3005514
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Reconstructed depth-resolved optic axis orientation obtained by catheter based PSOCT in a tissue volume informs on the orientation of the white matter fiber bundles in the brain, owing to the birefringence of myelinated axons. The physical organization of white matter also leads to anisotropic diffusion of water molecules, which is the basis of dMRI for non-invasive imaging of the three-dimensional orientation of white matter fiber bundles. Having access to fiber orientation in both imaging modalities, we are trying to map the depth-resolved birefringence and optic axis orientation to the larger scale dMRI as well as an atlas of brain anatomy.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Shadi Masoumi, Georgia Jones, Mireille Quemener, Martin Parent, Martin Villiger, Daniel Cote, and Maxina Sheft "Imaging and mapping local neuroanatomy surrounding a deep brain polarization-sensitive OCT catheter", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128302H (13 March 2024); https://doi.org/10.1117/12.3005514

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KEYWORDS

Brain

Neuroimaging

Brain mapping

Optical coherence tomography

Biological imaging

Electrodes

White matter

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