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1 March 2007 Probing the low-frequency vibrational modes of viruses with Raman scattering—bacteriophage M13 in water
Kong-Thon Tsen, Eric C. Dykeman, Otto F. Sankey, Shaw-Wei D. Tsen, Nien-Tsung Lin, Juliann G. Kiang
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Journal of Biomedical Optics, Vol. 12, Issue 2, 024009 (March 2007). https://doi.org/10.1117/1.2718935
Abstract
Raman spectroscopy is used to study low-wave-number (≤20 cm-1) acoustic vibrations of the M13 phage. A well-defined Raman line is observed at around 8.5 cm-1. The experimental results are compared with theoretical calculations based on an elastic continuum model and appropriate Raman selection rules derived from a bond polarizability model. The observed Raman mode is shown to belong to one of the Raman-active axial modes of the M13 phage protein coat. It is expected that the detection and characterization of this low-frequency vibrational mode can be used for applications in biomedical nanotechnology such as for monitoring the process of virus functionalization and self-assembly.
©(2007) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Kong-Thon Tsen, Eric C. Dykeman, Otto F. Sankey, Shaw-Wei D. Tsen, Nien-Tsung Lin, and Juliann G. Kiang "Probing the low-frequency vibrational modes of viruses with Raman scattering—bacteriophage M13 in water," Journal of Biomedical Optics 12(2), 024009 (1 March 2007). https://doi.org/10.1117/1.2718935
Published: 1 March 2007
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Cited by 13 scholarly publications.
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KEYWORDS
Raman spectroscopy
Raman scattering
Viruses
Proteins
Thin film coatings
Polarizability
Polarization
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