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1 September 2008 Analysis of hollow-core photonic bandgap fibers for evanescent wave biosensing
Jian Sun, Chi-Chiu Chan, Yifan Zhang, Ping Shum
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Journal of Biomedical Optics, Vol. 13, Issue 5, 054048 (September 2008). https://doi.org/10.1117/1.2983676
Abstract
Hollow-core photonic bandgap fiber (HC-PBGF)–based evanescent wave biosensors are demonstrated and analyzed theoretically and experimentally. With 95% of the guided light power residing in the samples, the measured absorbance for a 30-cm-long fiber filled with a 0.2 μM Alexa Fluor 700–labeled DNA Oligo solution is 1.06. This is in good agreement with the theoretical prediction, which is evaluated by using the refractive index scaling law. The HC-PBGFs thus offer both efficiency and simplicity for the detection of biomolecules in ultra-small sample volumes.
©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Jian Sun, Chi-Chiu Chan, Yifan Zhang, and Ping Shum "Analysis of hollow-core photonic bandgap fibers for evanescent wave biosensing," Journal of Biomedical Optics 13(5), 054048 (1 September 2008). https://doi.org/10.1117/1.2983676
Published: 1 September 2008
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Cited by 11 scholarly publications.
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KEYWORDS
Optical fibers
Refractive index
Water
Biological research
Absorption
Biosensors
Waveguides
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