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1 March 2009 Three-dimensional pointwise comparison of human retinal optical property at 845 and 1060 nm using optical frequency domain imaging
Yueli Chen, Daina L. Burnes, Martijn D. de Bruin, Mircea Mujat, Johannes F. de Boer
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Journal of Biomedical Optics, Vol. 14, Issue 2, 024016 (March 2009). https://doi.org/10.1117/1.3119103
Abstract
To compare the optical properties of the human retina, 3-D volumetric images of the same eye are acquired with two nearly identical optical coherence tomography (OCT) systems at center wavelengths of 845 and 1060 nm using optical frequency domain imaging (OFDI). To characterize the contrast of individual tissue layers in the retina at these two wavelengths, the 3-D volumetric data sets are carefully spatially matched. The relative scattering intensities from different layers such as the nerve fiber, photoreceptor, pigment epithelium, and choroid are measured and a quantitative comparison is presented. OCT retinal imaging at 1060 nm is found to have a significantly better depth penetration but a reduced contrast between the retinal nerve fiber, the ganglion cell, and the inner plexiform layers compared to the OCT retinal imaging at 845 nm.
©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Yueli Chen, Daina L. Burnes, Martijn D. de Bruin, Mircea Mujat, and Johannes F. de Boer "Three-dimensional pointwise comparison of human retinal optical property at 845 and 1060 nm using optical frequency domain imaging," Journal of Biomedical Optics 14(2), 024016 (1 March 2009). https://doi.org/10.1117/1.3119103
Published: 1 March 2009
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KEYWORDS
Optical coherence tomography
Scattering
Optical properties
Image segmentation
Retina
3D image processing
Retinal scanning
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