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1 September 2009 Doppler optical microangiography improves the quantification of local fluid flow and shear stress within 3-D porous constructs
Yali Jia, Lin An, Ruikang K. Wang
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Journal of Biomedical Optics, Vol. 14, Issue 5, 050504 (September 2009). https://doi.org/10.1117/1.3233590
Abstract
Traditional phase-resolved Doppler optical coherence tomography (DOCT) has been reported to have potential for characterizing local fluid flow within a microporous scaffold. In this work, we apply Doppler optical microangiography (DOMAG), a new imaging technique developed by combining optical microangiography (OMAG) with a phase-resolved method, for improved assessment of local fluid flow and its derived parameters, shear stress, and interconnectivity, within highly scattering porous constructs. Compared with DOCT, we demonstrate a dramatic improvement of DOMAG in quantifying flow-related properties within scaffolds in situ for functional tissue engineering.
©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Yali Jia, Lin An, and Ruikang K. Wang "Doppler optical microangiography improves the quantification of local fluid flow and shear stress within 3-D porous constructs," Journal of Biomedical Optics 14(5), 050504 (1 September 2009). https://doi.org/10.1117/1.3233590
Published: 1 September 2009
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Cited by 6 scholarly publications.
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KEYWORDS
Microfluidics
Microfluidic imaging
Tissue optics
Tissues
Doppler tomography
Interference (communication)
Scattering
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