Open Access
1 January 2010 Doppler optical coherence tomography for interventional cardiovascular guidance: in vivo feasibility and forward-viewing probe flow phantom demonstration
Nigel R. Munce, Graham A. Wright, Adrian Mariampillai, Beau A. Standish, Michael K. K. Leung, Louis Tan, Kenneth K.C. Lee, Brian K. Courtney M.D., Aaron A. Teitelbaum, Bradley H. Strauss M.D., I. Alex Vitkin, Victor Xiao Dong Yang
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Abstract
We demonstrate the potential of a forward-looking Doppler optical coherence tomography (OCT) probe for color flow imaging in several commonly seen narrowed artery morphologies. As a proof of concept, we present imaging results of a surgically exposed thrombotic occlusion model that was imaged superficially to demonstrate that Doppler OCT can identify flow within the recanalization channels of a blocked artery. We present Doppler OCT images in which the flow is nearly antiparallel to the imaging direction. These images are acquired using a flexible 2.2-mm-diam catheter that used electrostatic actuation to scan up to 30 deg ahead of the distal end. Doppler OCT images of physiologically relevant flow phantoms consisting of small channels and tapered entrance geometries are demonstrated.
©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
Nigel R. Munce, Graham A. Wright, Adrian Mariampillai, Beau A. Standish, Michael K. K. Leung, Louis Tan, Kenneth K.C. Lee, Brian K. Courtney M.D., Aaron A. Teitelbaum, Bradley H. Strauss M.D., I. Alex Vitkin, and Victor Xiao Dong Yang "Doppler optical coherence tomography for interventional cardiovascular guidance: in vivo feasibility and forward-viewing probe flow phantom demonstration," Journal of Biomedical Optics 15(1), 011103 (1 January 2010). https://doi.org/10.1117/1.3292007
Published: 1 January 2010
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CITATIONS
Cited by 11 scholarly publications.
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KEYWORDS
Optical coherence tomography

Doppler tomography

Arteries

In vivo imaging

Image segmentation

Doppler effect

Imaging systems

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