Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in the anterior chamber

Yong Zhou; Nan Zeng; Yanhong Ji; Yao Li; Xiangsong Dai; Peng Li; Lian Duan; Hui Ma; Yonghong He

doi:10.1117/1.3528658

1 January 2011 Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in the anterior chamber

Yong Zhou, Nan Zeng, Yanhong Ji, Yao Li, Xiangsong Dai, Peng Li, Lian Duan, Hui Ma, Yonghong He

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Journal of Biomedical Optics, Vol. 16, Issue 1, 015004 (January 2011). https://doi.org/10.1117/1.3528658

Abstract

We present a method of glucose concentration detection in the anterior chamber with a differential absorption optical low-coherent interferometry (LCI) technique. Back-reflected light from the iris, passing through the anterior chamber twice, was selectively obtained with the LCI technique. Two light sources, one centered within (1625 nm) and the other centered outside (1310 nm) of a glucose absorption band were used for differential absorption measurement. In the eye model and pig eye experiments, we obtained a resolution glucose level of 26.8 mg/dL and 69.6 mg/dL, respectively. This method has a potential application for noninvasive detection of glucose concentration in aqueous humor, which is related to the glucose concentration in blood.

©(2011) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Yong Zhou, Nan Zeng, Yanhong Ji, Yao Li, Xiangsong Dai, Peng Li, Lian Duan, Hui Ma, and Yonghong He "Iris as a reflector for differential absorption low-coherence interferometry to measure glucose level in the anterior chamber," Journal of Biomedical Optics 16(1), 015004 (1 January 2011). https://doi.org/10.1117/1.3528658

Published: 1 January 2011

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