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21 October 2013 Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display
Jiawen Li, Teng Ma, Joseph C. Jing, Jun Zhang, Pranav M. Patel, Koping Kirk Shung, Qifa Zhou, Zhongping Chen
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Journal of Biomedical Optics, Vol. 18, Issue 10, 100502 (October 2013). https://doi.org/10.1117/1.JBO.18.10.100502
Abstract
We have developed a novel miniature integrated optical coherence tomography (OCT)-intravascular ultrasound (IVUS) probe, with a 1.5-mm-long rigid part and 0.9-mm outer diameter, for real-time intracoronary imaging of atherosclerotic plaques and guiding of interventional procedures. By placing the OCT ball lens and IVUS transducer back-to-back at the same axial position, this probe can provide automatically coregistered, coaxial OCT-IVUS imaging. To demonstrate its real-time capability, three-dimensional OCT-IVUS imaging of a pig’s coronary artery displaying in polar coordinates, as well as images of three major types of atherosclerotic plaques in human cadaver coronary segments, were obtained using this probe and our upgraded system. Histology validation is also presented.
© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2013/$25.00 © 2013 SPIE
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Jiawen Li, Teng Ma, Joseph C. Jing, Jun Zhang, Pranav M. Patel, Koping Kirk Shung, Qifa Zhou, and Zhongping Chen "Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display," Journal of Biomedical Optics 18(10), 100502 (21 October 2013). https://doi.org/10.1117/1.JBO.18.10.100502
Published: 21 October 2013
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Cited by 40 scholarly publications and 2 patents.
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KEYWORDS
Optical coherence tomography
Intravascular ultrasound
Imaging systems
Arteries
Transducers
Image segmentation
Real time imaging
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