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23 January 2013 Fluorescence molecular tomography of an animal model using structured light rotating view acquisition
Nicolas Ducros, Andrea Bassi, Gianluca Valentini, Gianfranco L. Canti, Simon R. Arridge, Cosimo D'Andrea
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Journal of Biomedical Optics, Vol. 18, Issue 2, 020503 (January 2013). https://doi.org/10.1117/1.JBO.18.2.020503
Abstract
In recent years, an increasing effort has been devoted to the optimization of acquisition and reconstruction schemes for fluorescence molecular tomography (FMT). In particular, wide-field structured illumination and compression of the measured images have enabled significant reduction of the data set and, consequently, a decrease in both acquisition and processing times. FMT based on this concept has been recently demonstrated on a cylindrical phantom with a rotating-view scheme that significantly increases the reconstruction quality. In this work, we generalize the rotating-view scheme to arbitrary geometries and experimentally demonstrate its applicability to murine models. To the best of our knowledge this is the first time that FMT based on a rotating-view scheme with structured illumination and image compression has been applied to animals.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Nicolas Ducros, Andrea Bassi, Gianluca Valentini, Gianfranco L. Canti, Simon R. Arridge, and Cosimo D'Andrea "Fluorescence molecular tomography of an animal model using structured light rotating view acquisition," Journal of Biomedical Optics 18(2), 020503 (23 January 2013). https://doi.org/10.1117/1.JBO.18.2.020503
Published: 23 January 2013
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Cited by 42 scholarly publications.
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KEYWORDS
Luminescence
Animal model studies
Tomography
Fluorescence tomography
Structured light
Image compression
Data acquisition
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