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27 March 2013 Compact high power barium nitrite crystal-based Raman laser at 1197 nm for photoacoustic imaging of fat
Rui Li, Mikhail N. Slipchenko, Pu Wang, Ji-Xin Cheng
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Journal of Biomedical Optics, Vol. 18, Issue 4, 040502 (March 2013). https://doi.org/10.1117/1.JBO.18.4.040502
Abstract
Photoacoustic imaging employing molecular overtone vibration as a contrast mechanism opens a new avenue for bond-selective imaging of deep tissues. Broad use of this modality is, however, hampered by the extremely low conversion efficiency of optical parametric oscillators at the overtone transition wavelengths. To overcome such a barrier, we demonstrate the construction and use of a compact, barium nitrite crystal-based Raman laser for photoacoustic imaging of C–H overtone vibrations. Using a 5-ns Nd∶YAG laser as the pumping source, up to 21.4 mJ pulse energy at 1197 nm was generated, corresponding to a conversion efficiency of 34.8%. Using the 1197 nm pulses, three-dimensional photoacoustic imaging of intramuscular fat was demonstrated.
© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2013/$25.00 © 2013 SPIE
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Rui Li, Mikhail N. Slipchenko, Pu Wang, and Ji-Xin Cheng "Compact high power barium nitrite crystal-based Raman laser at 1197 nm for photoacoustic imaging of fat," Journal of Biomedical Optics 18(4), 040502 (27 March 2013). https://doi.org/10.1117/1.JBO.18.4.040502
Published: 27 March 2013
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Cited by 27 scholarly publications.
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KEYWORDS
Raman spectroscopy
Laser crystals
Crystals
Photoacoustic imaging
Barium
Energy efficiency
Neodymium
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