Dr. Vladimir A. Hovhannisyan Profile

Dr. Vladimir A. Hovhannisyan

SPIE Involvement:

Author

Publications (32)

Proceedings Article | 16 March 2020 Presentation + Paper

Investigation of adsorption and release of photodynamic dyes by Clinoptilolite zeolite

Anupama Nair, V. Hovhannisyan, Shean-Jen Chen

Proceedings Volume 11220, 112200G (2020) https://doi.org/10.1117/12.2546905

KEYWORDS: Skin, Zeolites, Luminescence, Adsorption, Tissues, Photodynamic therapy, Second-harmonic generation, Multiphoton microscopy, Biomedical optics, Particles

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Proceedings Article | 31 July 2019 Paper

Improved and fast biotissue imaging by temporal focusing widefield multiphoton microscopy with spatially modulated illumination

Chia-Yuan Chang, Chun-Yu Lin, Vladimir Hovhannisyan, Shean-Jen Chen

Proceedings Volume 11076, 110760G (2019) https://doi.org/10.1117/12.2526908

KEYWORDS: Modulation, Digital micromirror devices, Multiphoton microscopy, Scattering, Objectives, Microscopy, Diffraction, Spatial frequencies, Microscopes, Luminescence

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Proceedings Article | 22 July 2019 Paper

Zeolite magnetic nano/micro-particles for adsorption, delivery and release of photodynamic dyes

Vladimir Hovhannisyan, Katarina Siposova, Andrej Musatov, Zuzana Mitroova, Shean-Jen Chen

Proceedings Volume 11075, 110751G (2019) https://doi.org/10.1117/12.2526924

KEYWORDS: Magnetism, Zeolites, Adsorption, Luminescence, Multiphoton microscopy, Nanoparticles

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Proceedings Article | 22 February 2019 Paper

In vivo multiphoton dynamic imaging of the hepatobiliary metabolism in chronic hepatic diseases

Hsu-Cheng Huang, Chih-Ju Lin, Sheng-Lin Lee, Wei-Hsiang Wang, Vladimir A. Hovhannisyan, Yao-De Huang, Hsuan-Shu Lee, Chen-Yuan Dong

Proceedings Volume 10882, 108821B (2019) https://doi.org/10.1117/12.2507345

KEYWORDS: Liver, Mode conditioning cables, In vivo imaging, Tumors, Pathology, Tumor growth modeling, Molecules, Mouse models, Luminescence, Multiphoton microscopy

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Proceedings Article | 13 February 2017 Presentation + Paper

Hypericin-mediated selective photomodification of connective tissues

V. Hovhannisyan, A. Hovhannisyan, V. Ghukasyan, H. W. Guo, Hung-Ming Lin, S. J. Chen, Yang-Fang Chen, Chen-Yuan Dong

Proceedings Volume 10037, 100370O (2017) https://doi.org/10.1117/12.2255028

KEYWORDS: Tissues, Collagen, Luminescence, Second-harmonic generation, Ultraviolet radiation, Skin, Lamps, Halogens, Photodynamic therapy, Visible radiation

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Proceedings Article | 13 February 2017 Paper

Direct visualization of functional heterogeneity in hepatobiliary metabolism

Chih-Ju Lin, Feng-Chieh Li, Yu-Yang Lee, Te-Yu Tseng, Wei-Lian Chen, Vladimir Hovhannisyan, Ning Kang, Nicholas Horton, Shu-Jen Chiang, Chris Xu, Hsuan-Shu Lee, Chen-Yuan Dong

Proceedings Volume 10046, 100460C (2017) https://doi.org/10.1117/12.2254952

KEYWORDS: Visualization, Mode conditioning cables, Liver, Luminescence, Blood, Image processing, In vivo imaging, Two photon excitation microscopy, Veins, Plasma

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Proceedings Article | 18 June 2013 Paper

Enhanced multiphoton microscopy of bilogical tissue with optical clearing

Vladimir Hovhannisyan, Ara Ghazaryan, Pu-Sheng Hu, Chang-Seok Kim, Chen-Yuan Dong

Proceedings Volume 8798, 87980E (2013) https://doi.org/10.1117/12.2032734

KEYWORDS: Collagen, Second-harmonic generation, Tissue optics, Multiphoton microscopy, Optical clearing, Biomedical optics, Tissues, Light scattering, Molecules, Signal processing

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SPIE Journal Paper | 2 April 2013 Open Access

Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging

Vladimir Hovhannisyan, Po-Sheng Hu, Shean-Jen Chen, Chang-Seok Kim, Chen-Yuan Dong

JBO, Vol. 18, Issue 04, 046004, (April 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.4.046004

KEYWORDS: Collagen, Second-harmonic generation, Tissue optics, Tissues, Optical clearing, Skin, Signal processing, Molecules, Scattering, Transparency

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Proceedings Article | 11 December 2012 Paper

Collagen fiber spatial orientation mapping using polarization-sensitive SHG microscopy

Vladimir Hovhannisyan, Po-Sheng Hu, Chen-Yuan Dong

Proceedings Volume 8553, 855312 (2012) https://doi.org/10.1117/12.999982

KEYWORDS: Second-harmonic generation, Collagen, Polarization, Fiber lasers, Tissues, Associative arrays, Microscopy, Cornea, Structured optical fibers, Biological research

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SPIE Journal Paper | 22 November 2012 Open Access

Imaging of biological tissues with pixel-level analysis of second-order susceptibility

Po-Sheng Hu, Ara Ghazaryan, Vladimir Hovhannisyan, Shean-Jen Chen, Yang-Fang Chen, Chang-Seok Kim, Tsung-Hua Tsai, Chen-Yuan Dong

JBO, Vol. 18, Issue 03, 031102, (November 2012) https://doi.org/10.1117/12.10.1117/1.JBO.18.3.031102

KEYWORDS: Second-harmonic generation, Tissues, Collagen, Microscopy, Biological research, Polarization, Skin, Cartilage, Optical fibers, Imaging systems

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Proceedings Article | 9 June 2011 Paper

Dynamic multiphoton imaging of reversible and irreversible thermal changes in collagen tissues

Vladimir Hovhannisyan, Ping-Jung Su, Chen-Yuan Dong

Proceedings Volume 8087, 808710 (2011) https://doi.org/10.1117/12.890023

KEYWORDS: Second-harmonic generation, Collagen, Tissues, Skin, Temperature metrology, Microscopy, Spectroscopy, Thermodynamics, Proteins, Harmonic generation

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Proceedings Article | 9 June 2011 Paper

Characterization of the correlation between collagen fibril thickness and forward and backward second harmonic signal

Chiu-Mei Hsueh, Vladimir Hovhannisyan, Chen-Yuan Dong

Proceedings Volume 8086, 808616 (2011) https://doi.org/10.1117/12.889761

KEYWORDS: Collagen, Second-harmonic generation, Microscopy, Biomedical optics, Physics, Harmonic generation, In vivo imaging, Signal generators, Proteins, Bandpass filters

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Proceedings Article | 17 February 2011 Paper

Multiphoton imaging and quantification of tissue glycation

Ara Ghazaryan, Jo-Ya Tseng, Wen Lo, Yang-Fang Chen, Vladimir Hovhannisyan, Shean-Jen Chen, Hsin-Yuan Tan, Chen-Yuan Dong

Proceedings Volume 7895, 789509 (2011) https://doi.org/10.1117/12.874536

KEYWORDS: Tissues, Sclera, Multiphoton microscopy, Tissue optics, Cornea, Collagen, Skin, Harmonic generation, Second-harmonic generation, Microscopy

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SPIE Journal Paper | 1 May 2010 Open Access

Ex vivo imaging and quantification of liver fibrosis using second-harmonic generation microscopy

Tzu-Lin Sun, Yuan Liu, Ming-Chin Sung, Hsiao-Ching Chen, Chun-Hui Yang, Vladimir Hovhannisyan, Wei-Chou Lin, Yung-Ming Jeng, Wei-Liang Chen, Ling-Ling Chiou, Guan-Tarn Huang, Ki Hean Kim, Peter So, Yang-Fang Chen, Hsuan-Shu Lee, Chen-Yuan Dong

JBO, Vol. 15, Issue 03, 036002, (May 2010) https://doi.org/10.1117/12.10.1117/1.3427146

KEYWORDS: Liver, Second-harmonic generation, Collagen, Tissues, Multiphoton microscopy, Objectives, Physics, In vivo imaging, Imaging systems, Microscopy

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Proceedings Article | 3 March 2010 Paper

Characterization of corneal edema by forward and backward second harmonic generation microscopy

Chiu-Mei Hsueh, Wen Lo, Wei-Liang Chen, Vladimir Hovhannisyan, Hsin-Yuan Tan, Chen-Yuan Dong

Proceedings Volume 7550, 75501M (2010) https://doi.org/10.1117/12.843181

KEYWORDS: Cornea, Second-harmonic generation, Harmonic generation, Microscopy, Collagen, Mirrors, Signal detection, Physics, Microscopes, Medicine

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Proceedings Article | 23 February 2010 Paper

Human hepatocellular carcinoma diagnosis by multiphoton autofluorescence microscopy

Tzu-Lin Sun, Yuan Liu, Ming-Chin Sung, Hsiao-Ching Chen, Chuen-Huei Yang, Vladimir Hovhannisyan, Ling-Ling Chiou, Wei-Chou Lin, Guan-Tarn Huang, Ki-Hean Kim, Peter So, Chih-Ju Lin, Hsuan-Shu Lee, Chen-Yuan Dong

Proceedings Volume 7555, 75551L (2010) https://doi.org/10.1117/12.843157

KEYWORDS: Tissues, Liver, Second-harmonic generation, Multiphoton microscopy, Quantitative analysis, Tumors, Diagnostics, Physics, Signal processing, Microscopy

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Proceedings Article | 12 February 2010 Paper

Differentiation of normal and cancerous lung tissues by multiphoton imaging

Chun-Chin Wang, Feng-Chieh Li, Ruei-Jr Wu, Vladimir Hovhannisyan, Wei-Chou Lin, Sung-Jan Lin, Peter T. So, Chen-Yuan Dong

Proceedings Volume 7561, 756112 (2010) https://doi.org/10.1117/12.843173

KEYWORDS: Tissues, Lung, Second-harmonic generation, Lung cancer, Multiphoton microscopy, Cancer, Tumors, Collagen, Luminescence, Optical microscopy

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SPIE Journal Paper | 1 September 2009 Open Access

Multimodal, multiphoton microscopy and image correlation analysis for characterizing corneal thermal damage

Wen Lo, Yu-Lin Chang, Jia-Shiu Liu, Chiu-Mei Hseuh, Vladimir Hovhannisyan, Shean-Jen Chen, Hsian-Yuan Tan, Chen-Yuan Dong

JBO, Vol. 14, Issue 05, 054003, (September 2009) https://doi.org/10.1117/12.10.1117/1.3213602

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Proceedings Article | 17 July 2009 Paper

Non-ablative processing of biofibers by femtosecond IR laser

Vladimir Hovhannisyan, Wen Lo, Chieh Hu, Shean-Jen Chen, Chen Yuan Dong

Proceedings Volume 7373, 73731X (2009) https://doi.org/10.1117/12.831898

KEYWORDS: Collagen, Optical fibers, Femtosecond phenomena, Second-harmonic generation, Laser applications, Tissues, Infrared lasers, Skin, Laser cutting, Harmonic generation

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SPIE Journal Paper | 1 July 2009 Open Access

Differentiation of normal and cancerous lung tissues by multiphoton imaging

Chun-Chin Wang, Feng-Chieh Li, Ruei-Jr Wu, Vladimir Hovhannisyan, Wei-Chou Lin, Sung-Jan Lin, Peter So, Chen-Yuan Dong

JBO, Vol. 14, Issue 04, 044034, (July 2009) https://doi.org/10.1117/12.10.1117/1.3210768

KEYWORDS: Tissues, Lung, Second-harmonic generation, Lung cancer, Cancer, Optical fibers, Multiphoton microscopy, Tumors, Collagen, Roads

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SPIE Journal Paper | 1 September 2008 Open Access

Label-free imaging of Drosophila larva by multiphoton autofluorescence and second harmonic generation microscopy

Chiao-Ying Lin, Vladimir Hovhannisyan, June-Tai Wu, Chii-Wann Lin, Jyh-Horng Chen, Sung-Jan Lin, Chen-Yuan Dong

JBO, Vol. 13, Issue 05, 050502, (September 2008) https://doi.org/10.1117/12.10.1117/1.2981817

KEYWORDS: Second-harmonic generation, Multiphoton microscopy, In vivo imaging, Imaging systems, Harmonic generation, Microscopy, Organisms, Biology, Digestive system, Auto-fluorescence imaging

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SPIE Journal Paper | 1 July 2008 Open Access

Characterization of optical-aberration-induced lateral and axial image inhomogeneity in multiphoton microscopy

Vladimir Hovhannisyan, Ping-Jung Su, Chen-Yuan Dong

JBO, Vol. 13, Issue 04, 044023, (July 2008) https://doi.org/10.1117/12.10.1117/1.2950314

KEYWORDS: Refractive index, Point spread functions, Multiphoton microscopy, Second-harmonic generation, Monochromatic aberrations, Signal attenuation, Liquids, Biomedical optics, Harmonic generation, Imaging systems

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Proceedings Article | 14 March 2008 Paper

Multiphoton autofluorescence and second-harmonic generation diagnosis of hepatocellular carcinoma

Yuan Liu, Tzu-Lin Sun, Chuen-Huei Yang, Vladimir Hovhannisyan, Wei-Chou Lin, Hsuan-Shu Lee, Chen-Yuan Dong

Proceedings Volume 6863, 68630J (2008) https://doi.org/10.1117/12.764276

KEYWORDS: Second-harmonic generation, Multiphoton microscopy, Liver, Biopsy, Tissues, Tumors, Harmonic generation, Microscopes, Physics, Diagnostics

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Proceedings Article | 15 February 2008 Paper

Label-free in vivo imaging of Drosophila melanogaster by multiphoton microscopy

Chiao-Ying Lin, Vladimir Hovhannisyan, June-Tai Wu, Sung-Jan Lin, Chii-Wann Lin, Jyh-Horng Chen, Chen-Yuan Dong

Proceedings Volume 6860, 686019 (2008) https://doi.org/10.1117/12.763202

KEYWORDS: Multiphoton microscopy, Microscopy, Second-harmonic generation, Genetics, Biology, Organisms, In vivo imaging, Tissues, Biomedical optics, Confocal microscopy

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Proceedings Article | 8 October 2005 Paper

Combined pulse-oximeter-NIRS system for biotissue diagnostics

Vladimir Hovhannisyan

Proceedings Volume 5859, 58591M (2005) https://doi.org/10.1117/12.632885

KEYWORDS: Near infrared spectroscopy, Tissues, Oxygen, Diagnostics, Blood, Medicine, Absorption, Chromophores, Brain, Infrared spectroscopy

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Proceedings Article | 8 April 2005 Paper

Temperature effects in photodynamic processes

Vladimir Hovhannisyan, Hasmik Avetisyan, Margarita Mathevosyan, Egishe Elbakyan

Proceedings Volume 5689, (2005) https://doi.org/10.1117/12.586132

KEYWORDS: Photodynamic therapy, Temperature metrology, Lamps, Light emitting diodes, Absorption, Halogens, Solar radiation models, Cell death, Toxicity, Aluminum

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Proceedings Article | 26 October 2001 Paper

Novel diagnostic method for the detection of far-red fluorescence emission from several tumor-seeking photosensitizers

Theodossis Theodossiou, Vladimir Hovhannisyan, P. Kastaniotis, Konstantine Politopoulos, Dido Yova

Proceedings Volume 4433, (2001) https://doi.org/10.1117/12.446511

KEYWORDS: Luminescence, Glasses, Tissues, Tissue optics, Natural surfaces, Fluorescence spectroscopy, Absorption, Diagnostics, Photodynamic therapy, Magnesium

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SPIE Journal Paper | 1 January 2001 Open Access

Photochemical effects and hypericin photosensitized processes in collagen

Dido Yova, Vladimir Hovhannisyan, Theodossis Theodossiou

JBO, Vol. 6, Issue 01, (January 2001) https://doi.org/10.1117/12.10.1117/1.1331559

KEYWORDS: Collagen, Luminescence, Chromophores, Laser irradiation, Visible radiation, Ultraviolet radiation, Absorption, Photodynamic therapy, Skin, Tumors

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Proceedings Article | 16 November 2000 Paper

Broadly tunable optical harmonic generation in type I collagen using IR nanosecond laser pulses

Theodossis Theodossiou, Efstratios Georgiou, Vladimir Hovhannisyan, Konstantine Politopoulos, Georgia Rapti, Dido Yova

Proceedings Volume 4161, (2000) https://doi.org/10.1117/12.409310

KEYWORDS: Collagen, Second-harmonic generation, Harmonic generation, Tissue optics, Upconversion, Nd:YAG lasers, Signal detection, Nonlinear optics, Scattering, Biomedical optics

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Proceedings Article | 30 December 1999 Paper

Multifrequency Nd:YAG laser application for tumor fluorescence diagnosis

Dido Yova, Konstantinos Halkiotis, Athanassios Manolopoulos, Nikolaos Ouzounoglou, Vladimir Hovhannisyan, Lia Avanessian

Proceedings Volume 4059, (1999) https://doi.org/10.1117/12.375250

KEYWORDS: Luminescence, Tumors, Tissues, Nd:YAG lasers, Tissue optics, Laser tissue interaction, Laser systems engineering, Computing systems, Absorption, Animal model studies

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Proceedings Article | 4 January 1999 Paper

Photoinduced effect of hypericin on collagen and tissues with high collagen content

Dido Yova, Theodossis Theodossiou, Vladimir Hovhannisyan

Proceedings Volume 3565, (1999) https://doi.org/10.1117/12.335800

KEYWORDS: Collagen, Luminescence, Tissues, Second-harmonic generation, Arteries, Nd:YAG lasers, Harmonic generation, Skin, Hydrogen, Laser irradiation

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Proceedings Article | 29 December 1997 Paper

Effect of chlorin e6 and photosensitizer-superoxide dismutase complexes on ion-transporting processes of blood cells

Grigor Gyulkhandanyan, Anatoly Losev, Armen Gyulkhandanyan, Vladimir Hovhannisyan, Hakop Karagulyan, Margarita Korkhmazyan

Proceedings Volume 3191, (1997) https://doi.org/10.1117/12.297820

KEYWORDS: Blood, Oxygen, Absorption, Ultraviolet radiation, Luminescence, Ions

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Showing 5 of 32 publications

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