A response of HeLa Kyoto tumor cells on a combination of photobiomodulation and ionizing radiation

Elena I. Cherkasova; Ksenia V. Babak; Arteom O. Belotelov; Yulia L. Labutina; Vladimir I. Yusupov; Natalia N. Vorobieva; Anastasia S. Nerush; Anna V. Maslennikova

doi:10.1117/12.2577792

5 March 2021 A response of HeLa Kyoto tumor cells on a combination of photobiomodulation and ionizing radiation

Elena I. Cherkasova, Ksenia V. Babak, Arteom O. Belotelov, Yulia L. Labutina, Vladimir I. Yusupov, Natalia N. Vorobieva, Anastasia S. Nerush, Anna V. Maslennikova

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Proceedings Volume 11628, Mechanisms and Techniques in Photodynamic Therapy and Photobiomodulation; 116280J (2021) https://doi.org/10.1117/12.2577792
Event: SPIE BiOS, 2021, Online Only

Abstract

The aim of the work was studying the effects of photobiomodulation in doses of less than 1 J/cm2 in combination with gamma-irradiation to Hela Kyoto cells. Tumor cells were irradiated with 640 nm LED at different energy densities before and after to gamma-irradiation. Cells viability was determined 24 h after exposure for each gamma-irradiation dose and PBM mode. There was a statistically significant decrease in a number of viable tumor cells for samples that were exposed to PBM prior to gamma-irradiation and a statistically significant increase in a number of viable tumor cells for samples that were exposed to PBM after gamma-irradiation.

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Elena I. Cherkasova, Ksenia V. Babak, Arteom O. Belotelov, Yulia L. Labutina, Vladimir I. Yusupov, Natalia N. Vorobieva, Anastasia S. Nerush, and Anna V. Maslennikova "A response of HeLa Kyoto tumor cells on a combination of photobiomodulation and ionizing radiation", Proc. SPIE 11628, Mechanisms and Techniques in Photodynamic Therapy and Photobiomodulation, 116280J (5 March 2021); https://doi.org/10.1117/12.2577792

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