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5 March 2021 Infrared modulation of ionic and water dynamics of astroglial cells
Ana I. Borrachero-Conejo, Wilson R. Adams, Emanuela Saracino, Tamara Posati, Maria G. Mola, Grazia P. Nicchia, Valentina Benfenati, Anita Mahadevan-Jansen
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Proceedings Volume 11640, Optical Interactions with Tissue and Cells XXXII; 116400A (2021) https://doi.org/10.1117/12.2583139
Event: SPIE BiOS, 2021, Online Only
Abstract
Astrocytes play a critical role in regulating brain physiology at ionic, synaptic and whole-organ level. Their function is mainly controlled by ionic signalings, in particular Ca2+ signaling, that mediate cell-cell communication. Infrared pulsed stimulation is a label-free tool that has been previously used to modulate neuronal firing. Here we present the use of infrared pulsed light to stimulate ionic astrocytic signaling in order to modulate astroglial physiology. We present infrared pulsed stimulation as a powerful technique to understand astrocytic function and dysfunction.
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Ana I. Borrachero-Conejo, Wilson R. Adams, Emanuela Saracino, Tamara Posati, Maria G. Mola, Grazia P. Nicchia, Valentina Benfenati, and Anita Mahadevan-Jansen "Infrared modulation of ionic and water dynamics of astroglial cells", Proc. SPIE 11640, Optical Interactions with Tissue and Cells XXXII, 116400A (5 March 2021); https://doi.org/10.1117/12.2583139
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KEYWORDS
Infrared radiation
Modulation
Brain
Pathology
Ions
Ischemia
Luminescence
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