Tumor detection using time-resolved light transillumination

Roger Berg; Stefan Andersson-Engels; Olof Jarlman M.D.; Sune Svanberg

doi:10.1117/12.48209

1 November 1991 Tumor detection using time-resolved light transillumination

Roger Berg, Stefan Andersson-Engels, Olof Jarlman M.D., Sune Svanberg

Proceedings Volume 1525, Future Trends in Biomedical Applications of Lasers; (1991) https://doi.org/10.1117/12.48209
Event: MedTech '91, 1991, Berlin, Germany

Abstract

A time-gated technique to reduce the effect of light scattering when transilluminating turbid media such as tissue is demonstrated. The concept is based on transillumination with picosecond laser pulses and time-resolved detection. By detecting only the photons with the shortest travelling time, and thus the least scattered photons, the contrast can be enhanced. Measurements on a tissue phantom as well as breast tissue in vitro are presented. It is demonstrated that the spatial resolution can be enhanced by using the time-gated technique. It is also shown that differences in scattering properties may be more pronounced than differences in absorption properties when demarcating tumor from normal tissue.

Citation Download Citation

Roger Berg, Stefan Andersson-Engels, Olof Jarlman M.D., and Sune Svanberg "Tumor detection using time-resolved light transillumination", Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); https://doi.org/10.1117/12.48209

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