Short-pulse laser propagation through tissues

Champak Das; Ashish Trivedi; Kunal Mitra; Tuan Vo-Dinh

doi:10.1117/12.497340

22 July 2003 Short-pulse laser propagation through tissues

Champak Das, Ashish Trivedi, Kunal Mitra, Tuan Vo-Dinh

Proceedings Volume 4958, Advanced Biomedical and Clinical Diagnostic Systems; (2003) https://doi.org/10.1117/12.497340
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

An experimental and numerical study is performed to analyze short pulse laser propagation through tissue phantoms without and with inhomogeneities / tumors imbedded in it. Short pulse laser probing techniques has distinct advantages over conventional very large pulse width or cw lasers primarily due to the additional information conveyed about the tissue interior by the temporal variation of the observed signal. Both the scattered temporal transmitted and reflected optical signals are measured experimentally using a streak camera for samples irradiated with a short pulse laser source. Parametric study involving different scattering and absorption coefficients of tissue phantoms and inhomogeneities as well as the detector position and orientation is performed. The temporal and spatial profiles of the scattered optical signals are compared with the numerical modeling results obtained by solving the transient radiative transport equation using discrete ordinates technique.

Citation Download Citation

Champak Das, Ashish Trivedi, Kunal Mitra, and Tuan Vo-Dinh "Short-pulse laser propagation through tissues", Proc. SPIE 4958, Advanced Biomedical and Clinical Diagnostic Systems, (22 July 2003); https://doi.org/10.1117/12.497340

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